About Fibroleukin
Fibroleukin (FGL2) is a protein
from Homo sapiens identified by UniProt accession
Q14314, 439 residues long.
MolForge cross-references it against 0 known binders and
311 disease associations.
Target properties
| Protein name | Fibroleukin |
|---|
| UniProt accession | Q14314 |
|---|
| Gene | FGL2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 439 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (311)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- autoinflammatory syndrome · score 0.18
- waist-hip ratio · score 0.13
- neoplasm · score 0.12
- acute myeloid leukemia · score 0.11
- infect · score 0.09
- infection · score 0.09
- drug use measurement · score 0.09
- colitis · score 0.09
- colorectal carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14314-F1 | alphafold | PREDICTED | 78.71 | — |
Amino-acid sequence (439 residues)
MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDVCP VRLESRGKCE EAGECPYQVS LPPLTIQLPK QFSRIEEVFK EVQNLKEIVN SLKKSCQDCK LQADDNGDPG RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCPSQEQI QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNSSFEV YCDMETMGGG WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL RIDLEDFNGV ELYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN HDLKFFTTPD KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG VRNGIFWGTW PGVSEAHPGG YKSSFKEAKM MIRPKHFKP
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