About Protein FAM50A
Protein FAM50A (FAM50A) is a protein
from Homo sapiens identified by UniProt accession
Q14320, 339 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Protein FAM50A |
|---|
| UniProt accession | Q14320 |
|---|
| Gene | FAM50A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 339 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- Armfield syndrome · score 0.72
- complex neurodevelopmental disorder · score 0.37
- genetic disorder · score 0.33
- Intellectual disability · score 0.27
- neurodegenerative disease · score 0.20
- breast carcinoma · score 0.15
- hepatocellular carcinoma · score 0.07
- neoplasm · score 0.07
- cancer · score 0.04
- ovarian carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14320-F1 | alphafold | PREDICTED | 75.88 | — |
Amino-acid sequence (339 residues)
MAQYKGAASE AGRAMHLMKK REKQREQMEQ MKQRIAEENI MKSNIDKKFS AHYDAVEAEL KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQSKELQMK LEKLREKERK KEAKRKISSL SFTLEEEEEG GEEEEEAAMY EEEMEREEIT TKKRKLGKNP DVDTSFLPDR DREEEENRLR EELRQEWEAK QEKIKSEEIE ITFSYWDGSG HRRTVKMRKG NTMQQFLQKA LEILRKDFSE LRSAGVEQLM YIKEDLIIPH HHSFYDFIVT KARGKSGPLF NFDVHDDVRL LSDATVEKDE SHAGKVVLRS WYEKNKHIFP ASRWEPYDPE KKWDKYTIR
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