About Protein FRG1
Protein FRG1 (FRG1) is a protein
from Homo sapiens identified by UniProt accession
Q14331, 258 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Protein FRG1 |
|---|
| UniProt accession | Q14331 |
|---|
| Gene | FRG1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- albuminuria · score 0.32
- urinary albumin to creatinine ratio · score 0.26
- urinary microalbumin measurement · score 0.25
- Facioscapulohumeral dystrophy · score 0.21
- facioscapulohumeral muscular dystrophy · score 0.11
- neoplasm · score 0.09
- cancer · score 0.08
- anti-chlamydia trachomatis antibody measurement · score 0.03
- vascular disease · score 0.02
- Muscular dystrophy · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14331-F1 | alphafold | PREDICTED | 75.77 | — |
Amino-acid sequence (258 residues)
MAEYSYVKST KLVLKGTKTK SKKKKSKDKK RKREEDEETQ LDIVGIWWTV TNFGEISGTI AIEMDKGTYI HALDNGLFTL GAPHKEVDEG PSPPEQFTAV KLSDSRIALK SGYGKYLGIN SDGLVVGRSD AIGPREQWEP VFQNGKMALL ASNSCFIRCN EAGDIEAKSK TAGEEEMIKI RSCAERETKK KDDIPEEDKG NVKQCEINYV KKFQSFQDHK LKISKEDSKI LKKARKDGFL HETLLDRRAK LKADRYCK
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