About Histone RNA hairpin-binding protein
Histone RNA hairpin-binding protein (SLBP) is a protein
from Homo sapiens identified by UniProt accession
Q14493, 270 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | Histone RNA hairpin-binding protein |
|---|
| UniProt accession | Q14493 |
|---|
| Gene | SLBP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 270 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- lean body mass · score 0.19
- fat body mass · score 0.17
- osteoarthritis, hip · score 0.15
- mean corpuscular volume · score 0.15
- whole body water mass · score 0.15
- osteoarthritis, knee · score 0.15
- body height · score 0.14
- base metabolic rate measurement · score 0.13
- body weight · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14493-F1 | alphafold | PREDICTED | 70.00 | — |
Amino-acid sequence (270 residues)
MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPESF TTPEGPKPRS RCSDWASAVE EDEMRTRVNK EMARYKRKLL INDFGRERKS SSGSSDSKES MSTVPADFET DESVLMRRQK QINYGKNTIA YDRYIKEVPR HLRQPGIHPK TPNKFKKYSR RSWDQQIKLW KVALHFWDPP AEEGCDLQEI HPVDLESAES SSEPQTSSQD DFDVYSGTPT KVRHMDSQVE DEFDLEACLT EPLRDFSAMS
Explore Histone RNA hairpin-binding protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets