About Epididymal secretory protein E3-alpha
Epididymal secretory protein E3-alpha (EDDM3A) is a protein
from Homo sapiens identified by UniProt accession
Q14507, 147 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Epididymal secretory protein E3-alpha |
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| UniProt accession | Q14507 |
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| Gene | EDDM3A |
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| Organism | Homo sapiens |
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| Length | 147 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.09
- gonorrhea · score 0.07
- non-small cell lung carcinoma · score 0.07
- linear and whorled nevoid hypermelanosis · score 0.05
- neoplasm · score 0.05
- colorectal adenocarcinoma · score 0.04
- chronic myeloproliferative disorder · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- iridocorneal endothelial syndrome · score 0.04
- eosinophil peroxidase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14507-F1 | alphafold | PREDICTED | 91.25 | — |
Amino-acid sequence (147 residues)
MTSSLKIWGI LLALLCILCR LCVYSNNIYW REFIKLHYLS PSREFKEYKC DVLMREKEAL KGKSFHMFIY SLWFKIQRAC INEKGSDRYR NAYVWAPGAL KVLECHWEKY NNRYTESRSF SYIEFHCGVD GYVDNIEDLR IIEPISN
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