About Max dimerization protein 4
Max dimerization protein 4 (MXD4) is a protein
from Homo sapiens identified by UniProt accession
Q14582, 209 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Max dimerization protein 4 |
|---|
| UniProt accession | Q14582 |
|---|
| Gene | MXD4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 209 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- monocyte count · score 0.39
- high density lipoprotein cholesterol measurement · score 0.25
- systolic blood pressure · score 0.24
- diastolic blood pressure · score 0.22
- body weight · score 0.19
- acute myeloid leukemia · score 0.08
- lymphocyte count · score 0.07
- Brugada syndrome · score 0.05
- Familial progressive cardiac conduction defect · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14582-F1 | alphafold | PREDICTED | 71.75 | — |
Amino-acid sequence (209 residues)
MELNSLLILL EAAEYLERRD REAEHGYASV LPFDGDFARE KTKAAGLVRK APNNRSSHNE LEKHRRAKLR LYLEQLKQLV PLGPDSTRHT TLSLLKRAKV HIKKLEEQDR RALSIKEQLQ QEHRFLKRRL EQLSVQSVER VRTDSTGSAV STDDSEQEVD IEGMEFGPGE LDSVGSSSDA DDHYSLQSGT GGDSGFGPHC RRLGRPALS
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