Zinc finger protein 273 (ZNF273)

About Zinc finger protein 273

Zinc finger protein 273 (ZNF273) is a protein from Homo sapiens identified by UniProt accession Q14593, 569 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 273
UniProt accession	Q14593
Gene	ZNF273
Organism	Homo sapiens
Length	569 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

sleep duration · score 0.32
triglyceride measurement · score 0.32
neurodegenerative disease · score 0.25
protein measurement · score 0.03
psoriasis · score 0.02
squamous cell carcinoma · score 0.01
oral squamous cell carcinoma · score 0.01
Abnormal sperm morphology · score 0.01
acne · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14593-F1	alphafold	PREDICTED	69.87	—

Amino-acid sequence (569 residues)

MSSAPRGPPS VAPLPAGIGR STAKTPGLPG SLEMGPLTFR DVAIEFSLEE WQCLDTSQQN LYRNVMLDNY RNLVFLGIAV SKPDLITCLE QGKEPCNMKR HAMVAKPPVV CSHFAQDLWP KQGLKDSFQK VILRRYGKYG HENLQLRKGC KSADEHKVHK RGYNGLNQCL TTTQSKIFQC DKYVKVLHKF SNSNIHKKRQ TGKKPFKCKE CGKSCCILSQ LTQHKKTATR VNFYKCKTCG KAFNQFSNLT KHKIIHPEVN PYKCEECGKA FNQSLTLTKH KKIHTEEKPY KCEDCGKVFS VFSVLTKHKI IHTGTKPYNC EECGKGFSIF STLTKHKIIH TGEKPYKCNE CGKAFNWSST LTKHKRIHTG EKPYKCEECG KAFNQSSTLT RHKIVHTGEK PYKCEECGKA FKRSTTLTKH KRIYTKEKPY KCEECGKAFS VFSTLTKHKI IHTGAKPYKC EECGSAFRAF STLTEHKRVH TGEKPYKCNE CGKAFNWSST LTKHKRIHTG EKPYKCEECG KAFNRSSNLT RHKKIHTGEK PYKPKRCDSA FDNTPNFSRH KRNHMGEKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards