About Zinc finger protein 846
Zinc finger protein 846 (ZNF846) is a protein
from Homo sapiens identified by UniProt accession
Q147U1, 533 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Zinc finger protein 846 |
|---|
| UniProt accession | Q147U1 |
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| Gene | ZNF846 |
|---|
| Organism | Homo sapiens |
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| Length | 533 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (3)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- neoplasm · score 0.01
- spina bifida · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q147U1-F1 | alphafold | PREDICTED | 70.94 | — |
Amino-acid sequence (533 residues)
MDSSQHLVTF EDVAVDFTQE EWTLLDQAQR DLYRDVMLEN YKNLIILAGS ELFKRSLMSG LEQMEELRTG VTGVLQELDL QLKTKGSPLL QDISAERSPN GVQLERSNTA EKLYDSNHSG KVFNEHPFLM THMITHIGEK TSEDNQSGKA LRKNFPHSFY KKSHAEGKMP KCVKHEKAFN QFPNLTRQNK THTQEKLCEC KDCWRTFLNQ SSLKLHIRSH NGDKHYVCKE CGKAFSNSSH LIGHGRIHSG EKPYVCKECG KAFTQSTGLK LHIRTHSGEK PYKCKECGKA FTHSSYLTDH TRIHSGKKPY VCMECGKAFT RSTGLILHMR IHTGEKPYEC KECGKAFIHS SYLTKHVRIH SGEKLYLCKA CGKAFTRSSG LVLHMRTHTG EKPYECKECG KAFNNSSMLS QHVRIHTGEK PYECKECGKA FTQSSGLSTH LRTHTGEKAC ECKECGKAFA RSTNLNMHMR THTGEKPYAC KECGKAFRYS TYLNVHTRTH TGAKPYECKK CGKNFTQSSA LAKHLRTKAC EKT
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