FXYD domain-containing ion transport regulator 3…

About FXYD domain-containing ion transport regulator 3

FXYD domain-containing ion transport regulator 3 (FXYD3) is a protein from Homo sapiens identified by UniProt accession Q14802, 87 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein name	FXYD domain-containing ion transport regulator 3
UniProt accession	Q14802
Gene	FXYD3
Organism	Homo sapiens
Length	87 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (52)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.25
endometrial cancer · score 0.11
hepatocellular carcinoma · score 0.09
ulcerative colitis · score 0.08
calf circumference measurement · score 0.08
lung cancer · score 0.07
neoplasm · score 0.07
cancer · score 0.06
esophageal squamous cell carcinoma · score 0.05
psoriasis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14802-F1	alphafold	PREDICTED	68.25	—

Amino-acid sequence (87 residues)

MQKVTLGLLV FLAGFPVLDA NDLEDKNSPF YYDWHSLQVG GLICAGVLCA MGIIIVMSAK CKCKFGQKSG HHPGETPPLI TPGSAQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

FXYD domain-containing ion transport regulator 3 (FXYD3)