About Sodium-dependent phosphate transport protein 1
Sodium-dependent phosphate transport protein 1 (SLC17A1) is a protein
from Homo sapiens identified by UniProt accession
Q14916, 467 residues long.
MolForge cross-references it against 0 known binders and
111 disease associations.
Target properties
| Protein name | Sodium-dependent phosphate transport protein 1 |
|---|
| UniProt accession | Q14916 |
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| Gene | SLC17A1 |
|---|
| Organism | Homo sapiens |
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| Length | 467 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (111)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.44
- urinary metabolite measurement · score 0.42
- gout · score 0.42
- uric acid measurement · score 0.40
- serum metabolite measurement · score 0.39
- blood metabolite measurement · score 0.33
- rheumatoid arthritis · score 0.26
- drug use measurement · score 0.25
- joint disease · score 0.24
- reactive arthritis · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14916-F1 | alphafold | PREDICTED | 86.73 | — |
Amino-acid sequence (467 residues)
MQMDNRLPPK KVPGFCSFRY GLSFLVHCCN VIITAQRACL NLTMVVMVNS TDPHGLPNTS TKKLLDNIKN PMYNWSPDIQ GIILSSTSYG VIIIQVPVGY FSGIYSTKKM IGFALCLSSV LSLLIPPAAG IGVAWVVVCR AVQGAAQGIV ATAQFEIYVK WAPPLERGRL TSMSTSGFLL GPFIVLLVTG VICESLGWPM VFYIFGACGC AVCLLWFVLF YDDPKDHPCI SISEKEYITS SLVQQVSSSR QSLPIKAILK SLPVWAISTG SFTFFWSHNI MTLYTPMFIN SMLHVNIKEN GFLSSLPYLF AWICGNLAGQ LSDFFLTRNI LSVIAVRKLF TAAGFLLPAI FGVCLPYLSS TFYSIVIFLI LAGATGSFCL GGVFINGLDI APRYFGFIKA CSTLTGMIGG LIASTLTGLI LKQDPESAWF KTFILMAAIN VTGLIFYLIV ATAEIQDWAK EKQHTRL
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