Dr1-associated corepressor (DRAP1)

About Dr1-associated corepressor

Dr1-associated corepressor (DRAP1) is a protein from Homo sapiens identified by UniProt accession Q14919, 205 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Dr1-associated corepressor
UniProt accession	Q14919
Gene	DRAP1
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

serum urea measurement · score 0.03
triple-negative breast cancer · score 0.02
nonpapillary renal cell carcinoma · score 0.01
cancer · score 0.01
infect · score 0.00
infection · score 0.00
neoplasm · score 0.00
hepatocellular carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14919-F1	alphafold	PREDICTED	73.30	—

Amino-acid sequence (205 residues)

MPSKKKKYNA RFPPARIKKI MQTDEEIGKV AAAVPVIISR ALELFLESLL KKACQVTQSR NAKTMTTSHL KQCIELEQQF DFLKDLVASV PDMQGDGEDN HMDGDKGARR GRKPGSGGRK NGGMGTKSKD KKLSGTDSEQ EDESEDTDTD GEEETSQPPP QASHPSAHFQ SPPTPFLPFA STLPLPPAPP GPSAPDEEDE EDYDS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards