About Outer dense fiber protein 1
Outer dense fiber protein 1 (ODF1) is a protein
from Homo sapiens identified by UniProt accession
Q14990, 250 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | Outer dense fiber protein 1 |
|---|
| UniProt accession | Q14990 |
|---|
| Gene | ODF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 250 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (122)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.41
- platelet component distribution width · score 0.30
- chronic lymphocytic leukemia · score 0.28
- IGA glomerulonephritis · score 0.28
- systolic blood pressure · score 0.28
- serum IgM measurement · score 0.27
- age at menopause · score 0.27
- gut microbiome measurement · score 0.26
- total blood protein measurement · score 0.24
- azoospermia · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14990-F1 | alphafold | PREDICTED | 62.08 | — |
Amino-acid sequence (250 residues)
MAALSCLLDS VRRDIKKVDR ELRQLRCIDE FSTRCLCDLY MHPYCCCDLH PYPYCLCYSK RSRSCGLCDL YPCCLCDYKL YCLRPSLRSL ERKAIRAIED EKRELAKLRR TTNRILASSC CSSNILGSVN VCGFEPDQVK VRVKDGKVCV SAERENRYDC LGSKKYSYMN ICKEFSLPPC VDEKDVTYSY GLGSCVKIES PCYPCTSPCS PCSPCSPCNP CSPCNPCSPY DPCNPCYPCG SRFSCRKMIL
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