Solute carrier family 68 member 1 (SLC68A1)

About Solute carrier family 68 member 1

Solute carrier family 68 member 1 (SLC68A1) is a protein from Homo sapiens identified by UniProt accession Q14CX5, 517 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Solute carrier family 68 member 1
UniProt accession	Q14CX5
Gene	SLC68A1
Organism	Homo sapiens
Length	517 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

platelet crit · score 0.26
risk-taking behaviour · score 0.25
leukocyte count · score 0.24
neutrophil count · score 0.19
mean corpuscular hemoglobin concentration · score 0.18
insomnia · score 0.17
allergic rhinitis · score 0.14
platelet count · score 0.13
myeloid white cell count · score 0.13
alkaline phosphatase measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14CX5-F1	alphafold	PREDICTED	81.68	—

Amino-acid sequence (517 residues)

MGLGQPQAWL LGLPTAVVYG SLALFTTILH NVFLLYYVDT FVSVYKINKM AFWVGETVFL LWNSLNDPLF GWLSDRQFLS SQPRSGAGLS SRAVVLARVQ ALGWHGPLLA LSFLAFWVPW APAGLQFLLC LCLYDGFLTL VDLHHHALLA DLALSAHDRT HLNFYCSLFS AAGSLSVFAS YAFWNKEDFS SFRAFCVTLA VSSGLGFLGA TQLLRRRVEA ARKDPGCSGL VVDSGLCGEE LLVGSEEADS ITLGRYLRQL ARHRNFLWFV SMDLVQVFHC HFNSNFFPLF LEHLLSDHIS LSTGSILLGL SYVAPHLNNL YFLSLCRRWG VYAVVRGLFL LKLGLSLLML LAGPDHLSLL CLFIASNRVF TEGTCKLLTL VVTDLVDEDL VLNHRKQAAS ALLFGMVALV TKPGQTFAPL LGTWLLCFYT GHDLFQQSLI TPVGSAHPWP EPPAPAPAQA PTLRQGCFYL LVLVPITCAL LQLFTWSQFT LHGRRLHMVK AQRQNLSQAQ TLDVKMV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards