About FAST kinase domain-containing protein 3, mitochondrial
FAST kinase domain-containing protein 3, mitochondrial (FASTKD3) is a protein
from Homo sapiens identified by UniProt accession
Q14CZ7, 662 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | FAST kinase domain-containing protein 3, mitochondrial |
|---|
| UniProt accession | Q14CZ7 |
|---|
| Gene | FASTKD3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 662 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- mean corpuscular volume · score 0.22
- mean corpuscular hemoglobin concentration · score 0.17
- fasting blood insulin measurement · score 0.16
- mean corpuscular hemoglobin · score 0.15
- self reported educational attainment · score 0.13
- HbA1c measurement · score 0.12
- PHF-tau measurement · score 0.11
- body height · score 0.05
- adolescent idiopathic scoliosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14CZ7-F1 | alphafold | PREDICTED | 81.65 | — |
Amino-acid sequence (662 residues)
MALITLRKNL YRLSDFQMHR ALAALKNKPL NHVHKVVKER LCPWLCSRQP EPFGVKFHHA HCKKFHSKNG NDLHPLGGPV FSQVSDCDRL EQNVKNEESQ MFYRRLSNLT SSEEVLSFIS TMETLPDTMA AGALQRICEV EKKDGDQGLP KEILENSIFQ ALCFQFEKEP SQLSNTSLVT ALQALILLHV DPQSSLLLNL VAECQNRLRK GGMEVRNLCI LGESLITLHS SGCVTLELII NQLQGEKLET FTPEDIVALY RILQACTEKV DEHQTFLNKI NNFSLSIVSN LSPKLISQML TALVVLDQSQ AFPLIIKLGK YVVRHVPHFT NEELRRVLEA FIYFGHHDTF FTKALEHRVA AVCLTLDPEV VCRVMEYCSR ELILSKPILN AVAETFVCQT EKFSPRQISA LMEPFGKLNY LPPNASALFR KLENVLFTHF NYFPPKSLLK LLHSCSLNEC HPVNFLAKIF KPLFLQRLQG KESHLDTLSR AQLTQLFLAS VLECPFYKGP KLLPKYQVKS FLTPCCSLET PVDSQLYRYV KIGLTNLLGA RLYFAPKVLT PYCYTIDVEI KLDEEGFVLP STANEDIHKR IALCIDGPKR FCSNSKHLLG KEAIKQRHLQ LLGYQVVQIP YHEIGMLKSR RELVEYLQRK LFSQNTVHWL QE
Explore FAST kinase domain-containing protein 3, mitochondrial with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets