About Receptor-transporting protein 5
Receptor-transporting protein 5 (RTP5) is a protein
from Homo sapiens identified by UniProt accession
Q14D33, 572 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Receptor-transporting protein 5 |
|---|
| UniProt accession | Q14D33 |
|---|
| Gene | RTP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 572 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.32
- eosinophil percentage of leukocytes · score 0.21
- Eczematoid dermatitis · score 0.07
- asthma · score 0.07
- brain aneurysm · score 0.05
- Myopia · score 0.04
- age at onset · score 0.04
- refractive error · score 0.03
- brucellosis · score 0.02
- infect · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14D33-F1 | alphafold | PREDICTED | 47.50 | — |
Amino-acid sequence (572 residues)
MDRAGADMWA STFTLAMAER KPQDVWVLLP EHSLVPGCLD GGGVQYLLVG LSRLQCGHCP GTWDSAHVHV LFHLWWDRAS HRGLVKMRIW GQRCRLCPAP GDCQVRPPGE QPFLSRLVLH ILQDCYGDGP GPARHPREAY EGCCEACELG VCFLQKAPDP AWSANATKGN FPATAWGGTG TVSRGKPLST PGDDLGKGGV VIAIPFSLVG TSNDQVPIAE GPAPPAGASL PVTGSCEALV IGQGSIFLSG DSVAMPGGKG FPVAIGDPLF HGPGLLGSSI QTFELKGFLF KGRGSLCSPV GVAQGWGPIS LNNGLVPVGK HTPTVFYCVG LSASGEGSLT FPSSLTSIFT NTLSEPTDGP VATKEASITF PFIFTDVKDA VAEVAEGNGK EGGGQGLVPV GHDALPETNA GGLPSQVKGS LALPFPADVQ GKDAFTDITE GKEKEGGLVT AGHDAPLEAN AEGPITVSEG CITIPFAVFD VIKRKGGGHV AYGPQGNGCF SQGYYQKRQL RSRFHKARCG CRREEDERPG RACRRPHAEP YEDFWIWVSM TVCVFWLMCM CRLNPGIYPQ QV
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