MAD2L1-binding protein (MAD2L1BP)

Homo sapiens — UniProt Q15013

Gene: MAD2L1BPHomo sapiensSwissProt reviewed

About MAD2L1-binding protein

MAD2L1-binding protein (MAD2L1BP) is a protein from Homo sapiens identified by UniProt accession Q15013, 274 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein nameMAD2L1-binding protein
UniProt accessionQ15013
GeneMAD2L1BP
OrganismHomo sapiens
Length274 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.21
  • body weight · score 0.11
  • lean body mass · score 0.10
  • fat body mass · score 0.08
  • hemoglobin measurement · score 0.03
  • body fat percentage · score 0.02
  • female infertility · score 0.02
  • granulosa cell tumor · score 0.01
  • hepatocellular carcinoma · score 0.01
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q15013-F1alphafoldPREDICTED79.97—

Amino-acid sequence (274 residues)

MAAPEAEVLS SAAVPDLEWY EKSEETHASQ IELLETSSTQ EPLNASEAFC PRDCMVPVVF PGPVSQEGCC QFTCELLKHI MYQRQQLPLP YEQLKHFYRK PSPQAEEMLK KKPRATTEVS SRKCQQALAE LESVLSHLED FFARTLVPRV LILLGGNALS PKEFYELDLS LLAPYSVDQS LSTAACLRRL FRAIFMADAF SELQAPPLMG TVVMAQGHRN CGEDWFRPKL NYRVPSRGHK LTVTLSCGRP SIRTTAWEDY IWFQAPVTFK GFRE

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Quick facts

UniProtQ15013
GeneMAD2L1BP
OrganismHomo sapiens
Length274
Binders0
Diseases19
View on UniProt