About MAD2L1-binding protein
MAD2L1-binding protein (MAD2L1BP) is a protein
from Homo sapiens identified by UniProt accession
Q15013, 274 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | MAD2L1-binding protein |
| UniProt accession | Q15013 |
| Gene | MAD2L1BP |
| Organism | Homo sapiens |
| Length | 274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- body mass index · score 0.21
- body weight · score 0.11
- lean body mass · score 0.10
- fat body mass · score 0.08
- hemoglobin measurement · score 0.03
- body fat percentage · score 0.02
- female infertility · score 0.02
- granulosa cell tumor · score 0.01
- hepatocellular carcinoma · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q15013-F1 | alphafold | PREDICTED | 79.97 | — |
Amino-acid sequence (274 residues)
MAAPEAEVLS SAAVPDLEWY EKSEETHASQ IELLETSSTQ EPLNASEAFC PRDCMVPVVF PGPVSQEGCC QFTCELLKHI MYQRQQLPLP YEQLKHFYRK PSPQAEEMLK KKPRATTEVS SRKCQQALAE LESVLSHLED FFARTLVPRV LILLGGNALS PKEFYELDLS LLAPYSVDQS LSTAACLRRL FRAIFMADAF SELQAPPLMG TVVMAQGHRN CGEDWFRPKL NYRVPSRGHK LTVTLSCGRP SIRTTAWEDY IWFQAPVTFK GFRE
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