About Mortality factor 4-like protein 2
Mortality factor 4-like protein 2 (MORF4L2) is a protein
from Homo sapiens identified by UniProt accession
Q15014, 288 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Mortality factor 4-like protein 2 |
|---|
| UniProt accession | Q15014 |
|---|
| Gene | MORF4L2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 288 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- neoplasm · score 0.04
- Abnormal sperm morphology · score 0.02
- neuroendocrine neoplasm · score 0.01
- adenocarcinoma · score 0.01
- esophageal squamous cell carcinoma · score 0.01
- chronic kidney disease · score 0.01
- glioblastoma · score 0.01
- myeloid sarcoma · score 0.00
- Cognitive impairment · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15014-F1 | alphafold | PREDICTED | 73.34 | — |
Amino-acid sequence (288 residues)
MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL
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