Uncharacterized protein KIAA0040 (KIAA0040)

About Uncharacterized protein KIAA0040

Uncharacterized protein KIAA0040 (KIAA0040) is a protein from Homo sapiens identified by UniProt accession Q15053, 99 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Uncharacterized protein KIAA0040
UniProt accession	Q15053
Gene	KIAA0040
Organism	Homo sapiens
Length	99 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (39)

Diseases linked to this target (Open Targets).

diastolic blood pressure · score 0.39
neurodegenerative disease · score 0.37
PHF-tau measurement · score 0.35
FEV/FVC ratio · score 0.30
Red cell distribution width · score 0.29
migraine disorder · score 0.29
gut microbiome measurement · score 0.24
testosterone measurement · score 0.09
intelligence · score 0.09
wet macular degeneration · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15053-F1	alphafold	PREDICTED	69.50	—

Amino-acid sequence (99 residues)

MERISAFFSS IWDTILTKHQ EGIYNTICLG VLLGLPLLVI ITLLFICCHC CWSPPGKRGQ QPEKNKKKKK KKKKKDEEDL WISAQPKLLQ MEKRPSLPV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards