About Phosphoglucomutase-like protein 5
Phosphoglucomutase-like protein 5 (PGM5) is a protein
from Homo sapiens identified by UniProt accession
Q15124, 567 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Phosphoglucomutase-like protein 5 |
|---|
| UniProt accession | Q15124 |
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| Gene | PGM5 |
|---|
| Organism | Homo sapiens |
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| Length | 567 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.18
- red blood cell density measurement · score 0.17
- erythrocyte count · score 0.16
- hematocrit · score 0.12
- creatinine measurement · score 0.11
- cystatin C measurement · score 0.10
- blood phosphate measurement · score 0.10
- lung adenocarcinoma · score 0.08
- non-small cell lung carcinoma · score 0.08
- serum urea measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15124-F1 | alphafold | PREDICTED | 96.35 | — |
Amino-acid sequence (567 residues)
MEGSPIPVLT VPTAPYEDQR PAGGGGLRRP TGLFEGQRNY LPNFIQSVLS SIDLRDRQGC TMVVGSDGRY FSRTAIEIVV QMAAANGIGR LIIGQNGILS TPAVSCIIRK IKAAGGIILT ASHCPGGPGG EFGVKFNVAN GGPAPDVVSD KIYQISKTIE EYAICPDLRI DLSRLGRQEF DLENKFKPFR VEIVDPVDIY LNLLRTIFDF HAIKGLLTGP SQLKIRIDAM HGVMGPYVRK VLCDELGAPA NSAINCVPLE DFGGQHPDPN LTYATTLLEA MKGGEYGFGA AFDADGDRYM ILGQNGFFVS PSDSLAIIAA NLSCIPYFRQ MGVRGFGRSM PTSMALDRVA KSMKVPVYET PAGWRFFSNL MDSGRCNLCG EESFGTGSDH LREKDGLWAV LVWLSIIAAR KQSVEEIVRD HWAKFGRHYY CRFDYEGLDP KTTYYIMRDL EALVTDKSFI GQQFAVGSHV YSVAKTDSFE YVDPVDGTVT KKQGLRIIFS DASRLIFRLS SSSGVRATLR LYAESYERDP SGHDQEPQAV LSPLIAIALK ISQIHERTGR RGPTVIT
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