About Transcription elongation factor A protein-like 1
Transcription elongation factor A protein-like 1 (TCEAL1) is a protein
from Homo sapiens identified by UniProt accession
Q15170, 159 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Transcription elongation factor A protein-like 1 |
|---|
| UniProt accession | Q15170 |
|---|
| Gene | TCEAL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with gait disturbance, dysmorphic facies, and behavioral abnormalities, X-linked · score 0.64
- genetic disorder · score 0.39
- neurodegenerative disease · score 0.30
- Neurodevelopmental disorder · score 0.19
- cancer · score 0.01
- nervous system disease · score 0.01
- infection · score 0.01
- infect · score 0.01
- neoplasm · score 0.01
- glioblastoma multiforme · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15170-F1 | alphafold | PREDICTED | 67.09 | — |
Amino-acid sequence (159 residues)
MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSPEEQSSE EQSSEEEFFP EELLPELLPE MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPI
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