Pregnancy-specific beta-1-glycoprotein 5 (PSG5)

Homo sapiens — UniProt Q15238

Gene: PSG5Homo sapiensSwissProt reviewed

About Pregnancy-specific beta-1-glycoprotein 5

Pregnancy-specific beta-1-glycoprotein 5 (PSG5) is a protein from Homo sapiens identified by UniProt accession Q15238, 335 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein namePregnancy-specific beta-1-glycoprotein 5
UniProt accessionQ15238
GenePSG5
OrganismHomo sapiens
Length335 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (99)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.40
  • glioblastoma multiforme · score 0.18
  • breast adenocarcinoma · score 0.18
  • multiple myeloma · score 0.17
  • thyroid gland adenocarcinoma · score 0.16
  • head and neck squamous cell carcinoma · score 0.11
  • anti-chlamydia trachomatis antibody measurement · score 0.08
  • ringed hair disease · score 0.08
  • Griscelli syndrome type 3 · score 0.08
  • uncombable hair syndrome · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q15238-F1alphafoldPREDICTED85.70—

Amino-acid sequence (335 residues)

MGPLSAPPCT QHITWKGLLL TASLLNFWNL PITAQVTIEA LPPKVSEGKD VLLLVHNLPQ NLAGYIWYKG QLMDLYHYIT SYVVDGQINI YGPAYTGRET VYSNASLLIQ NVTREDAGSY TLHIIKRGDR TRGVTGYFTF NLYLKLPKPY ITINNSKPRE NKDVLAFTCE PKSENYTYIW WLNGQSLPVS PRVKRPIENR ILILPSVTRN ETGPYECEIR DRDGGMRSDP VTLNVLYGPD LPSIYPSFTY YRSGENLYLS CFAESNPPAE YFWTINGKFQ QSGQKLSIPQ ITTKHRGLYT CSVRNSATGK ESSKSMTVEV SAPSGIGRLP LLNPI

Explore Pregnancy-specific beta-1-glycoprotein 5 with MolForge

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Quick facts

UniProtQ15238
GenePSG5
OrganismHomo sapiens
Length335
Binders0
Diseases99
View on UniProt