About Zinc finger MYND domain-containing protein 11
Zinc finger MYND domain-containing protein 11 (ZMYND11) is a protein
from Homo sapiens identified by UniProt accession
Q15326, 602 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Zinc finger MYND domain-containing protein 11 |
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| UniProt accession | Q15326 |
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| Gene | ZMYND11 |
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| Organism | Homo sapiens |
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| Length | 602 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (70)
Diseases linked to this target (Open Targets).
- Intellectual disability · score 0.61
- intellectual disability, autosomal dominant · score 0.57
- genetic disorder · score 0.52
- autosomal dominant non-syndromic intellectual disability · score 0.37
- Global developmental delay · score 0.34
- diet measurement · score 0.21
- brain measurement · score 0.15
- Neurodevelopmental disorder · score 0.12
- Motor delay · score 0.12
- Absent speech · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15326-F1 | alphafold | PREDICTED | 82.29 | — |
Amino-acid sequence (602 residues)
MARLTKRRQA DTKAIQHLWA AIEIIRNQKQ IANIDRITKY MSRVHGMHPK ETTRQLSLAV KDGLIVETLT VGCKGSKAGI EQEGYWLPGD EIDWETENHD WYCFECHLPG EVLICDLCFR VYHSKCLSDE FRLRDSSSPW QCPVCRSIKK KNTNKQEMGT YLRFIVSRMK ERAIDLNKKG KDNKHPMYRR LVHSAVDVPT IQEKVNEGKY RSYEEFKADA QLLLHNTVIF YGADSEQADI ARMLYKDTCH ELDELQLCKN CFYLSNARPD NWFCYPCIPN HELVWAKMKG FGFWPAKVMQ KEDNQVDVRF FGHHHQRAWI PSENIQDITV NIHRLHVKRS MGWKKACDEL ELHQRFLREG RFWKSKNEDR GEEEAESSIS STSNEQLKVT QEPRAKKGRR NQSVEPKKEE PEPETEAVSS SQEIPTMPQP IEKVSVSTQT KKLSASSPRM LHRSTQTTND GVCQSMCHDK YTKIFNDFKD RMKSDHKRET ERVVREALEK LRSEMEEEKR QAVNKAVANM QGEMDRKCKQ VKEKCKEEFV EEIKKLATQH KQLISQTKKK QWCYNCEEEA MYHCCWNTSY CSIKCQQEHW HAEHKRTCRR KR
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