About Elongin-C
Elongin-C (ELOC) is a protein
from Homo sapiens identified by UniProt accession
Q15369, 112 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Elongin-C |
|---|
| UniProt accession | Q15369 |
|---|
| Gene | ELOC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 112 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.59
- papillary renal cell carcinoma · score 0.35
- low density lipoprotein cholesterol measurement · score 0.25
- alkaline phosphatase measurement · score 0.22
- eosinophil count · score 0.19
- total cholesterol measurement · score 0.18
- mitochondrial proton-transporting ATP synthase complex deficiency · score 0.12
- Isolated ATP synthase deficiency · score 0.12
- lymphocyte count · score 0.10
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15369-F1 | alphafold | PREDICTED | 89.81 | — |
Amino-acid sequence (112 residues)
MDGEEKTYGG CEGPDAMYVK LISSDGHEFI VKREHALTSG TIKAMLSGPG QFAENETNEV NFREIPSHVL SKVCMYFTYK VRYTNSSTEI PEFPIAPEIA LELLMAANFL DC
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