Elongin-B (ELOB)

About Elongin-B

Elongin-B (ELOB) is a protein from Homo sapiens identified by UniProt accession Q15370, 118 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Elongin-B
UniProt accession	Q15370
Gene	ELOB
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

HIV infection · score 0.59
neuritic plaque measurement · score 0.12
forced expiratory volume · score 0.06
neoplasm · score 0.04
body mass index · score 0.03
cytomegalovirus infection · score 0.03
Abnormal sperm morphology · score 0.02
arterial stiffness measurement · score 0.02
triple-negative breast cancer · score 0.02
myxosarcoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15370-F1	alphafold	PREDICTED	92.47	—

Amino-acid sequence (118 residues)

MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPD EQRLYKDDQL LDDGKTLGEC GFTSQTARPQ APATVGLAFR ADDTFEALCI EPFSSPPELP DVMKPQDSGS SANEQAVQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards