About P2Y purinoceptor 14
P2Y purinoceptor 14 (P2RY14) is a protein
from Homo sapiens identified by UniProt accession
Q15391, 338 residues long.
MolForge cross-references it against 0 known binders and
168 disease associations.
Target properties
| Protein name | P2Y purinoceptor 14 |
|---|
| UniProt accession | Q15391 |
|---|
| Gene | P2RY14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 338 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (168)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.29
- eosinophil percentage of leukocytes · score 0.23
- cutaneous melanoma · score 0.13
- diverticular disease · score 0.11
- rectal disease · score 0.11
- breast adenocarcinoma · score 0.10
- lung adenocarcinoma · score 0.08
- mean platelet volume · score 0.08
- leukocyte count · score 0.08
- myeloid white cell count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15391-F1 | alphafold | PREDICTED | 87.10 | — |
Amino-acid sequence (338 residues)
MINSTSTQPP DESCSQNLLI TQQIIPVLYC MVFIAGILLN GVSGWIFFYV PSSKSFIIYL KNIVIADFVM SLTFPFKILG DSGLGPWQLN VFVCRVSAVL FYVNMYVSIV FFGLISFDRY YKIVKPLWTS FIQSVSYSKL LSVIVWMLML LLAVPNIILT NQSVREVTQI KCIELKSELG RKWHKASNYI FVAIFWIVFL LLIVFYTAIT KKIFKSHLKS SRNSTSVKKK SSRNIFSIVF VFFVCFVPYH IARIPYTKSQ TEAHYSCQSK EILRYMKEFT LLLSAANVCL DPIIYFFLCQ PFREILCKKL HIPLKAQNDL DISRIKRGNT TLESTDTL
Explore P2Y purinoceptor 14 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets