About Ras suppressor protein 1
Ras suppressor protein 1 (RSU1) is a protein
from Homo sapiens identified by UniProt accession
Q15404, 277 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Ras suppressor protein 1 |
|---|
| UniProt accession | Q15404 |
|---|
| Gene | RSU1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 277 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- body weight · score 0.33
- body fat percentage · score 0.33
- fat body mass · score 0.32
- platelet count · score 0.30
- albuminuria · score 0.29
- body mass index · score 0.29
- platelet component distribution width · score 0.29
- lean body mass · score 0.27
- platelet crit · score 0.25
- hip circumference · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15404-F1 | alphafold | PREDICTED | 94.91 | — |
Amino-acid sequence (277 residues)
MSKSLKKLVE ESREKNQPEV DMSDRGISNM LDVNGLFTLS HITQLVLSHN KLTMVPPNIA ELKNLEVLNF FNNQIEELPT QISSLQKLKH LNLGMNRLNT LPRGFGSLPA LEVLDLTYNN LSENSLPGNF FYLTTLRALY LSDNDFEILP PDIGKLTKLQ ILSLRDNDLI SLPKEIGELT QLKELHIQGN RLTVLPPELG NLDLTGQKQV FKAENNPWVT PIADQFQLGV SHVFEYIRSE TYKYLYGRHM QANPEPPKKN NDKSKKISRK PLAAKNR
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