About Calponin-3
Calponin-3 (CNN3) is a protein
from Homo sapiens identified by UniProt accession
Q15417, 329 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | Calponin-3 |
|---|
| UniProt accession | Q15417 |
|---|
| Gene | CNN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 329 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (85)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- fatty acid measurement · score 0.31
- diffuse plaque measurement · score 0.29
- gut microbiome measurement · score 0.19
- cigarettes per day measurement · score 0.12
- non-small cell lung carcinoma · score 0.08
- diffuse large B-cell lymphoma · score 0.07
- systemic scleroderma · score 0.07
- cancer · score 0.06
- neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15417-F1 | alphafold | PREDICTED | 67.71 | — |
Amino-acid sequence (329 residues)
MTHFNKGPSY GLSAEVKNKI ASKYDHQAEE DLRNWIEEVT GMSIGPNFQL GLKDGIILCE LINKLQPGSV KKVNESSLNW PQLENIGNFI KAIQAYGMKP HDIFEANDLF ENGNMTQVQT TLVALAGLAK TKGFHTTIDI GVKYAEKQTR RFDEGKLKAG QSVIGLQMGT NKCASQAGMT AYGTRRHLYD PKMQTDKPFD QTTISLQMGT NKGASQAGML APGTRRDIYD QKLTLQPVDN STISLQMGTN KVASQKGMSV YGLGRQVYDP KYCAAPTEPV IHNGSQGTGT NGSEISDSDY QAEYPDEYHG EYQDDYPRDY QYSDQGIDY
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