Protein phosphatase 1 regulatory subunit 7 (PPP1R7)

About Protein phosphatase 1 regulatory subunit 7

Protein phosphatase 1 regulatory subunit 7 (PPP1R7) is a protein from Homo sapiens identified by UniProt accession Q15435, 360 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Protein phosphatase 1 regulatory subunit 7
UniProt accession	Q15435
Gene	PPP1R7
Organism	Homo sapiens
Length	360 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.20
body height · score 0.09
essential hypertension · score 0.04
hypertension · score 0.04
neoplasm · score 0.03
acute myeloid leukemia · score 0.02
forced expiratory volume · score 0.02
body fat percentage · score 0.02
Abnormal sperm morphology · score 0.02
ovarian carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15435-F1	alphafold	PREDICTED	86.99	—

Amino-acid sequence (360 residues)

MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKLTRLKKLF LVNNKISKIE NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTELQE FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards