Cytohesin-1 (CYTH1)

About Cytohesin-1

Cytohesin-1 (CYTH1) is a protein from Homo sapiens identified by UniProt accession Q15438, 398 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein name	Cytohesin-1
UniProt accession	Q15438
Gene	CYTH1
Organism	Homo sapiens
Length	398 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (64)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.30
pulse pressure measurement · score 0.28
Parkinson disease · score 0.25
neurodegenerative disease · score 0.25
multiple sclerosis · score 0.25
lysosomal storage disease · score 0.25
Alzheimer disease · score 0.25
Red cell distribution width · score 0.25
body weight · score 0.23
ulcerative colitis · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15438-F1	alphafold	PREDICTED	84.31	—

Amino-acid sequence (398 residues)

MEEDDSYVPS DLTAEERQEL ENIRRRKQEL LADIQRLKDE IAEVANEIEN LGSTEERKNM QRNKQVAMGR KKFNMDPKKG IQFLIENDLL KNTCEDIAQF LYKGEGLNKT AIGDYLGERD EFNIQVLHAF VELHEFTDLN LVQALRQFLW SFRLPGEAQK IDRMMEAFAQ RYCQCNNGVF QSTDTCYVLS FAIIMLNTSL HNPNVKDKPT VERFIAMNRG INDGGDLPEE LLRNLYESIK NEPFKIPEDD GNDLTHTFFN PDREGWLLKL GGGRVKTWKR RWFILTDNCL YYFEYTTDKE PRGIIPLENL SIREVEDSKK PNCFELYIPD NKDQVIKACK TEADGRVVEG NHTVYRISAP TPEEKEEWIK CIKAAISRDP FYEMLAARKK KVSSTKRH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards