About Ficolin-2
Ficolin-2 (FCN2) is a protein
from Homo sapiens identified by UniProt accession
Q15485, 313 residues long.
MolForge cross-references it against 0 known binders and
210 disease associations.
Target properties
| Protein name | Ficolin-2 |
|---|
| UniProt accession | Q15485 |
|---|
| Gene | FCN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 313 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (210)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.47
- protein measurement · score 0.40
- neutrophil count · score 0.16
- urate measurement · score 0.15
- bone density · score 0.15
- myeloid white cell count · score 0.15
- leukocyte count · score 0.14
- cutaneous melanoma · score 0.12
- neutrophil percentage of leukocytes · score 0.12
- heel bone mineral density · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15485-F1 | alphafold | PREDICTED | 85.11 | — |
Amino-acid sequence (313 residues)
MELDRAVGVL GAATLLLSFL GMAWALQAAD TCPEVKMVGL EGSDKLTILR GCPGLPGAPG PKGEAGTNGK RGERGPPGPP GKAGPPGPNG APGEPQPCLT GPRTCKDLLD RGHFLSGWHT IYLPDCRPLT VLCDMDTDGG GWTVFQRRVD GSVDFYRDWA TYKQGFGSRL GEFWLGNDNI HALTAQGTSE LRVDLVDFED NYQFAKYRSF KVADEAEKYN LVLGAFVEGS AGDSLTFHNN QSFSTKDQDN DLNTGNCAVM FQGAWWYKNC HVSNLNGRYL RGTHGSFANG INWKSGKGYN YSYKVSEMKV RPA
Explore Ficolin-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets