About Regucalcin
Regucalcin (RGN) is a protein
from Homo sapiens identified by UniProt accession
Q15493, 299 residues long.
MolForge cross-references it against 0 known binders and
199 disease associations.
Target properties
| Protein name | Regucalcin |
|---|
| UniProt accession | Q15493 |
|---|
| Gene | RGN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 299 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (199)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.09
- non-small cell lung carcinoma · score 0.08
- diabetes mellitus · score 0.08
- neoplasm · score 0.07
- breast carcinoma · score 0.06
- breast cancer · score 0.06
- Cataract-microcornea syndrome · score 0.05
- Posterior polar cataract · score 0.05
- Alopecia universalis · score 0.05
- hypotrichosis simplex · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15493-F1 | alphafold | PREDICTED | 97.86 | — |
Amino-acid sequence (299 residues)
MSSIKIECVL PENCRCGESP VWEEVSNSLL FVDIPAKKVC RWDSFTKQVQ RVTMDAPVSS VALRQSGGYV ATIGTKFCAL NWKEQSAVVL ATVDNDKKNN RFNDGKVDPA GRYFAGTMAE ETAPAVLERH QGALYSLFPD HHVKKYFDQV DISNGLDWSL DHKIFYYIDS LSYSVDAFDY DLQTGQISNR RSVYKLEKEE QIPDGMCIDA EGKLWVACYN GGRVIRLDPV TGKRLQTVKL PVDKTTSCCF GGKNYSEMYV TCARDGMDPE GLLRQPEAGG IFKITGLGVK GIAPYSYAG
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