About Transcription initiation factor TFIID subunit 13
Transcription initiation factor TFIID subunit 13 (TAF13) is a protein
from Homo sapiens identified by UniProt accession
Q15543, 124 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Transcription initiation factor TFIID subunit 13 |
|---|
| UniProt accession | Q15543 |
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| Gene | TAF13 |
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| Organism | Homo sapiens |
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| Length | 124 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- intellectual disability, autosomal recessive 60 · score 0.64
- HIV infection · score 0.58
- neurodegenerative disease · score 0.55
- microcephaly-thin corpus callosum-intellectual disability syndrome · score 0.46
- autosomal recessive primary microcephaly · score 0.37
- breast adenocarcinoma · score 0.25
- lysosomal storage disease · score 0.17
- clear cell renal carcinoma · score 0.17
- small cell lung carcinoma · score 0.14
- genetic disorder · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15543-F1 | alphafold | PREDICTED | 82.47 | — |
Amino-acid sequence (124 residues)
MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL VIEFITEMTH KAMSIGRQGR VQVEDIVFLI RKDPRKFARV KDLLTMNEEL KRARKAFDEA NYGS
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