About Transcription initiation factor TFIID subunit 11
Transcription initiation factor TFIID subunit 11 (TAF11) is a protein
from Homo sapiens identified by UniProt accession
Q15544, 211 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Transcription initiation factor TFIID subunit 11 |
|---|
| UniProt accession | Q15544 |
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| Gene | TAF11 |
|---|
| Organism | Homo sapiens |
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| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.58
- neurodegenerative disease · score 0.49
- lysosomal storage disease · score 0.26
- breast adenocarcinoma · score 0.25
- esophageal cancer · score 0.15
- mean platelet volume · score 0.09
- reticulocyte count · score 0.07
- body mass index · score 0.06
- cystatin C measurement · score 0.06
- body height · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15544-F1 | alphafold | PREDICTED | 72.11 | — |
Amino-acid sequence (211 residues)
MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE AAAEEGELES QDVSDLTTVE REDSSLLNPA AKKLKIDTKE KKEKKQKVDE DEIQKMQILV SSFSEEQLNR YEMYRRSAFP KAAIKRLIQS ITGTSVSQNV VIAMSGISKV FVGEVVEEAL DVCEKWGEMP PLQPKHMREA VRRLKSKGQI PNSKHKKIIF F
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