Transcription elongation factor A protein 2 (TCEA2)

About Transcription elongation factor A protein 2

Transcription elongation factor A protein 2 (TCEA2) is a protein from Homo sapiens identified by UniProt accession Q15560, 299 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Transcription elongation factor A protein 2
UniProt accession	Q15560
Gene	TCEA2
Organism	Homo sapiens
Length	299 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.32
body mass index · score 0.31
Varicose veins · score 0.30
eosinophil count · score 0.29
neurodegenerative disease · score 0.28
lymphatic system disease · score 0.27
vein disorder · score 0.27
diastolic blood pressure · score 0.27
BMI-adjusted waist-hip ratio · score 0.26
anxiety measurement · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15560-F1	alphafold	PREDICTED	80.01	—

Amino-acid sequence (299 residues)

MMGKEEEIAR IARRLDKMVT KKSAEGAMDL LRELKAMPIT LHLLQSTRVG MSVNALRKQS SDEEVIALAK SLIKSWKKLL DASDAKARER GRGMPLPTSS RDASEAPDPS RKRPELPRAP STPRITTFPP VPVTCDAVRN KCREMLTAAL QTDHDHVAIG ADCERLSAQI EECIFRDVGN TDMKYKNRVR SRISNLKDAK NPDLRRNVLC GAITPQQIAV MTSEEMASDE LKEIRKAMTK EAIREHQMAR TGGTQTDLFT CGKCRKKNCT YTQVQTRSSD EPMTTFVVCN ECGNRWKFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards