Olfactory receptor 8B8 (OR8B8)

About Olfactory receptor 8B8

Olfactory receptor 8B8 (OR8B8) is a protein from Homo sapiens identified by UniProt accession Q15620, 311 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Olfactory receptor 8B8
UniProt accession	Q15620
Gene	OR8B8
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

clear cell renal carcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
breast carcinoma · score 0.01
diabetes mellitus · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15620-F1	alphafold	PREDICTED	89.88	—

Amino-acid sequence (311 residues)

MAAENSSFVT QFILAGLTDQ PGVQIPLFFL FLGFYVVTVV GNLGLITLIR LNSHLHTPMY FFLYNLSFID FCYSSVITPK MLMSFVLKKN SISYAGCMTQ LFFFLFFVVS ESFILSAMAY DRYVAICNPL LYMVTMSPQV CFLLLLGVYG MGFAGAMAHT ACMMGVTFCA NNLVNHYMCD ILPLLECACT STYVNELVVF VVVGIDIGVP TVTIFISYAL ILSSIFHIDS TEGRSKAFST CSSHIIAVSL FFGSGAFMYL KPFSLLAMNQ GKVSSLFYTT VVPMLNPLIY SLRNKDVKVA LKKILNKNAF S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards