About Translin
Translin (TSN) is a protein
from Homo sapiens identified by UniProt accession
Q15631, 228 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Translin |
|---|
| UniProt accession | Q15631 |
|---|
| Gene | TSN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- heart failure · score 0.34
- neurodegenerative disease · score 0.25
- obese body mass index status · score 0.24
- overweight body mass index status · score 0.24
- smoking status measurement · score 0.23
- irritability measurement · score 0.20
- Irritability · score 0.20
- retinal vein occlusion · score 0.19
- hypertension · score 0.19
- neuroticism measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15631-F1 | alphafold | PREDICTED | 92.51 | — |
Amino-acid sequence (228 residues)
MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK
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