About Zinc finger HIT domain-containing protein 3
Zinc finger HIT domain-containing protein 3 (ZNHIT3) is a protein
from Homo sapiens identified by UniProt accession
Q15649, 155 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Zinc finger HIT domain-containing protein 3 |
|---|
| UniProt accession | Q15649 |
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| Gene | ZNHIT3 |
|---|
| Organism | Homo sapiens |
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| Length | 155 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- PEHO syndrome · score 0.59
- PEHO-like syndrome · score 0.46
- neurodegenerative disease · score 0.42
- genetic disorder · score 0.18
- blood protein measurement · score 0.16
- Red cell distribution width · score 0.14
- CCL4 measurement · score 0.13
- C-C motif chemokine 3 measurement · score 0.13
- macrophage inflammatory protein 1b measurement · score 0.12
- urate measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15649-F1 | alphafold | PREDICTED | 74.59 | — |
Amino-acid sequence (155 residues)
MASLKCSTVV CVICLEKPKY RCPACRVPYC SVVCFRKHKE QCNPETRPVE KKIRSALPTK TVKPVENKDD DDSIADFLNS DEEEDRVSLQ NLKNLGESAT LRSLLLNPHL RQLMVNLDQG EDKAKLMRAY MQEPLFVEFA DCCLGIVEPS QNEES
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