CCAAT/enhancer-binding protein epsilon (CEBPE)

About CCAAT/enhancer-binding protein epsilon

CCAAT/enhancer-binding protein epsilon (CEBPE) is a protein from Homo sapiens identified by UniProt accession Q15744, 281 residues long. MolForge cross-references it against 0 known binders and 272 disease associations.

Target properties

Protein name	CCAAT/enhancer-binding protein epsilon
UniProt accession	Q15744
Gene	CEBPE
Organism	Homo sapiens
Length	281 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15744-F1	alphafold	PREDICTED	63.20	—

Amino-acid sequence (281 residues)

MSHGTYYECE PRGGQQPLEF SGGRAGPGEL GDMCEHEASI DLSAYIESGE EQLLSDLFAV KPAPEARGLK GPGTPAFPHY LPPDPRPFAY PPHTFGPDRK ALGPGIYSSP GSYDPRAVAV KEEPRGPEGS RAASRGSYNP LQYQVAHCGQ TAMHLPPTLA APGQPLRVLK APLATAAPPC SPLLKAPSPA GPLHKGKKAV NKDSLEYRLR RERNNIAVRK SRDKAKRRIL ETQQKVLEYM AENERLRSRV EQLTQELDTL RNLFRQIPEA ANLIKGVGGC S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards