Probable G-protein coupled receptor 19 (GPR19)

About Probable G-protein coupled receptor 19

Probable G-protein coupled receptor 19 (GPR19) is a protein from Homo sapiens identified by UniProt accession Q15760, 415 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.

Target properties

Protein name	Probable G-protein coupled receptor 19
UniProt accession	Q15760
Gene	GPR19
Organism	Homo sapiens
Length	415 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (77)

Diseases linked to this target (Open Targets).

forced expiratory volume · score 0.31
mean corpuscular hemoglobin · score 0.24
lean body mass · score 0.24
pulse pressure measurement · score 0.24
vital capacity · score 0.22
mathematical ability · score 0.21
body height · score 0.21
fat body mass · score 0.19
whole body water mass · score 0.19
mean corpuscular volume · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15760-F1	alphafold	PREDICTED	74.41	—

Amino-acid sequence (415 residues)

MVFAHRMDNS KPHLIIPTLL VPLQNRSCTE TATPLPSQYL MELSEEHSWM SNQTDLHYVL KPGEVATASI FFGILWLFSI FGNSLVCLVI HRSRRTQSTT NYFVVSMACA DLLISVASTP FVLLQFTTGR WTLGSATCKV VRYFQYLTPG VQIYVLLSIC IDRFYTIVYP LSFKVSREKA KKMIAASWVF DAGFVTPVLF FYGSNWDSHC NYFLPSSWEG TAYTVIHFLV GFVIPSVLII LFYQKVIKYI WRIGTDGRTV RRTMNIVPRT KVKTIKMFLI LNLLFLLSWL PFHVAQLWHP HEQDYKKSSL VFTAITWISF SSSASKPTLY SIYNANFRRG MKETFCMSSM KCYRSNAYTI TTSSRMAKKN YVGISEIPSM AKTITKDSIY DSFDREAKEK KLAWPINSNP PNTFV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards