About Neuropeptide Y receptor type 5
Neuropeptide Y receptor type 5 (NPY5R) is a protein
from Homo sapiens identified by UniProt accession
Q15761, 445 residues long.
MolForge cross-references it against 0 known binders and
106 disease associations.
Target properties
| Protein name | Neuropeptide Y receptor type 5 |
|---|
| UniProt accession | Q15761 |
|---|
| Gene | NPY5R |
|---|
| Organism | Homo sapiens |
|---|
| Length | 445 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (106)
Diseases linked to this target (Open Targets).
- obesity · score 0.36
- glioblastoma multiforme · score 0.26
- neurodegenerative disease · score 0.20
- fat body mass · score 0.19
- breast adenocarcinoma · score 0.17
- triglyceride measurement · score 0.17
- head and neck squamous cell carcinoma · score 0.16
- mathematical ability · score 0.15
- self reported educational attainment · score 0.14
- neuroblastoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15761-F1 | alphafold | PREDICTED | 75.66 | — |
Amino-acid sequence (445 residues)
MDLELDEYYN KTLATENNTA ATRNSDFPVW DDYKSSVDDL QYFLIGLYTF VSLLGFMGNL LILMALMKKR NQKTTVNFLI GNLAFSDILV VLFCSPFTLT SVLLDQWMFG KVMCHIMPFL QCVSVLVSTL ILISIAIVRY HMIKHPISNN LTANHGYFLI ATVWTLGFAI CSPLPVFHSL VELQETFGSA LLSSRYLCVE SWPSDSYRIA FTISLLLVQY ILPLVCLTVS HTSVCRSISC GLSNKENRLE ENEMINLTLH PSKKSGPQVK LSGSHKWSYS FIKKHRRRYS KKTACVLPAP ERPSQENHSR ILPENFGSVR SQLSSSSKFI PGVPTCFEIK PEENSDVHEL RVKRSVTRIK KRSRSVFYRL TILILVFAVS WMPLHLFHVV TDFNDNLISN RHFKLVYCIC HLLGMMSCCL NPILYGFLNN GIKADLVSLI HCLHM
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