About Myeloid leukemia factor 2
Myeloid leukemia factor 2 (MLF2) is a protein
from Homo sapiens identified by UniProt accession
Q15773, 248 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Myeloid leukemia factor 2 |
|---|
| UniProt accession | Q15773 |
|---|
| Gene | MLF2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.24
- insomnia measurement · score 0.16
- body height · score 0.16
- high density lipoprotein cholesterol measurement · score 0.15
- smoking status measurement · score 0.14
- Hearing abnormality · score 0.14
- red blood cell density measurement · score 0.05
- erythrocyte count · score 0.04
- BMI-adjusted hip circumference · score 0.03
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15773-F1 | alphafold | PREDICTED | 65.13 | — |
Amino-acid sequence (248 residues)
MFRFMRDVEP EDPMFLMDPF AIHRQHMSRM LSGGFGYSPF LSITDGNMPG TRPASRRMQQ AGAVSPFGML GMSGGFMDMF GMMNDMIGNM EHMTAGGNCQ TFSSSTVISY SNTGDGAPKV YQETSEMRSA PGGIRETRRT VRDSDSGLEQ MSIGHHIRDR AHILQRSRNH RTGDQEERQD YINLDESEAA AFDDEWRRET SRFRQQRPLE FRRLESSGAG GRRAEGPPRL AIQGPEDSPS RQSRRYDW
Explore Myeloid leukemia factor 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets