About Methylsterol monooxygenase 1
Methylsterol monooxygenase 1 (MSMO1) is a protein
from Homo sapiens identified by UniProt accession
Q15800, 293 residues long.
MolForge cross-references it against 0 known binders and
104 disease associations.
Target properties
| Protein name | Methylsterol monooxygenase 1 |
|---|
| UniProt accession | Q15800 |
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| Gene | MSMO1 |
|---|
| Organism | Homo sapiens |
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| Length | 293 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (104)
Diseases linked to this target (Open Targets).
- microcephaly-congenital cataract-psoriasiform dermatitis syndrome · score 0.80
- neurodegenerative disease · score 0.44
- heel bone mineral density · score 0.43
- adolescent idiopathic scoliosis · score 0.39
- blood protein measurement · score 0.31
- genetic disorder · score 0.30
- insulin resistance · score 0.29
- fasting blood insulin measurement · score 0.29
- vitamin D measurement · score 0.15
- cervical squamous cell carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15800-F1 | alphafold | PREDICTED | 93.84 | — |
Amino-acid sequence (293 residues)
MATNESVSIF SSASLAVEYV DSLLPENPLQ EPFKNAWNYM LNNYTKFQIA TWGSLIVHEA LYFLFCLPGF LFQFIPYMKK YKIQKDKPET WENQWKCFKV LLFNHFCIQL PLICGTYYFT EYFNIPYDWE RMPRWYFLLA RCFGCAVIED TWHYFLHRLL HHKRIYKYIH KVHHEFQAPF GMEAEYAHPL ETLILGTGFF IGIVLLCDHV ILLWAWVTIR LLETIDVHSG YDIPLNPLNL IPFYAGSRHH DFHHMNFIGN YASTFTWWDR IFGTDSQYNA YNEKRKKFEK KTE
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