Coiled-coil domain-containing protein 85B (CCDC85B)

About Coiled-coil domain-containing protein 85B

Coiled-coil domain-containing protein 85B (CCDC85B) is a protein from Homo sapiens identified by UniProt accession Q15834, 202 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 85B
UniProt accession	Q15834
Gene	CCDC85B
Organism	Homo sapiens
Length	202 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

monocyte count · score 0.04
Crohn's disease · score 0.03
Lyme disease · score 0.03
self reported educational attainment · score 0.02
non-small cell lung carcinoma · score 0.02
ovarian carcinoma · score 0.02
Alzheimer disease · score 0.01
cancer · score 0.01
primitive neuroectodermal tumor · score 0.01
Fever · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15834-F1	alphafold	PREDICTED	80.65	—

Amino-acid sequence (202 residues)

MEAEAGGLEE LTDEEMAALG KEELVRRLRR EEAARLAALV QRGRLMQEVN RQLQGHLGEI RELKQLNRRL QAENRELRDL CCFLDSERQR GRRAARQWQL FGTQASRAVR EDLGGCWQKL AELEGRQEEL LRENLALKEL CLALGEEWGP RGGPSGAGGS GAGPAPELAL PPCGPRDLGD GSSSTGSVGS PDQLPLACSP DD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards