Vesicle-associated membrane protein 3 (VAMP3)

About Vesicle-associated membrane protein 3

Vesicle-associated membrane protein 3 (VAMP3) is a protein from Homo sapiens identified by UniProt accession Q15836, 100 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.

Target properties

Protein name	Vesicle-associated membrane protein 3
UniProt accession	Q15836
Gene	VAMP3
Organism	Homo sapiens
Length	100 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (119)

Diseases linked to this target (Open Targets).

Alzheimer disease · score 0.28
neurodegenerative disease · score 0.28
Parkinson disease · score 0.28
multiple sclerosis · score 0.28
lysosomal storage disease · score 0.28
circadian rhythm · score 0.21
hematocrit · score 0.19
chronotype measurement · score 0.14
hemoglobin measurement · score 0.12
body mass index · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15836-F1	alphafold	PREDICTED	90.82	—

Amino-acid sequence (100 residues)

MSTGPTAATG SNRRLQQTQN QVDEVVDIMR VNVDKVLERD QKLSELDDRA DALQAGASQF ETSAAKLKRK YWWKNCKMWA IGITVLVIFI IIIIVWVVSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards