Clusterin-like protein 1 (CLUL1)

About Clusterin-like protein 1

Clusterin-like protein 1 (CLUL1) is a protein from Homo sapiens identified by UniProt accession Q15846, 466 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Clusterin-like protein 1
UniProt accession	Q15846
Gene	CLUL1
Organism	Homo sapiens
Length	466 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.37
mean corpuscular volume · score 0.21
Testicular Germ Cell Tumor · score 0.19
serum gamma-glutamyl transferase measurement · score 0.04
benign neoplasm · score 0.04
systolic blood pressure · score 0.03
protein measurement · score 0.02
urate measurement · score 0.02
bone density · score 0.02
drug use measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15846-F1	alphafold	PREDICTED	64.65	—

Amino-acid sequence (466 residues)

MKPPLLVFIV CLLWLKDSHC APTWKDKTAI SENLKSFSEV GEIDADEEVK KALTGIKQMK IMMERKEKEH TNLMSTLKKC REEKQEALKL LNEVQEHLEE EERLCRESLA DSWGECRSCL ENNCMRIYTT CQPSWSSVKN KIERFFRKIY QFLFPFHEDN EKDLPISEKL IEEDAQLTQM EDVFSQLTVD VNSLFNRSFN VFRQMQQEFD QTFQSHFISD TDLTEPYFFP AFSKEPMTKA DLEQCWDIPN FFQLFCNFSV SIYESVSETI TKMLKAIEDL PKQDKAPDHG GLISKMLPGQ DRGLCGELDQ NLSRCFKFHE KCQKCQAHLS EDCPDVPALH TELDEAIRLV NVSNQQYGQI LQMTRKHLED TAYLVEKMRG QFGWVSELAN QAPETEIIFN SIQVVPRIHE GNISKQDETM MTDLSILPSS NFTLKIPLEE SAESSNFIGY VVAKALQHFK EHFKTW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards