Adipogenesis regulatory factor (ADIRF)

About Adipogenesis regulatory factor

Adipogenesis regulatory factor (ADIRF) is a protein from Homo sapiens identified by UniProt accession Q15847, 76 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Adipogenesis regulatory factor
UniProt accession	Q15847
Gene	ADIRF
Organism	Homo sapiens
Length	76 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.08
osteosarcoma · score 0.07
body height · score 0.04
non-small cell lung carcinoma · score 0.03
bone density · score 0.02
urate measurement · score 0.02
atypical teratoid rhabdoid tumor · score 0.02
lung carcinoma · score 0.02
leukocyte count · score 0.02
heel bone mineral density · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q15847-F1	alphafold	PREDICTED	74.68	—

Amino-acid sequence (76 residues)

MASKGLQDLK QQVEGTAQEA VSAAGAAAQQ VVDQATEAGQ KAMDQLAKTT QETIDKTANQ ASDTFSGIGK KFGLLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards