About Adiponectin
Adiponectin (ADIPOQ) is a protein
from Homo sapiens identified by UniProt accession
Q15848, 244 residues long.
MolForge cross-references it against 0 known binders and
1,142 disease associations.
Target properties
| Protein name | Adiponectin |
|---|
| UniProt accession | Q15848 |
|---|
| Gene | ADIPOQ |
|---|
| Organism | Homo sapiens |
|---|
| Length | 244 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1142)
Diseases linked to this target (Open Targets).
- adiponectin measurement · score 0.43
- BMI-adjusted adiponectin measurement · score 0.39
- blood protein measurement · score 0.32
- gut microbiome measurement · score 0.24
- lung adenocarcinoma · score 0.19
- type 2 diabetes mellitus · score 0.15
- metabolic syndrome · score 0.13
- Obesity · score 0.12
- insulin resistance · score 0.12
- gestational diabetes · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15848-F1 | alphafold | PREDICTED | 79.89 | — |
Amino-acid sequence (244 residues)
MLLLGAVLLL LALPGHDQET TTQGPGVLLP LPKGACTGWM AGIPGHPGHN GAPGRDGRDG TPGEKGEKGD PGLIGPKGDI GETGVPGAEG PRGFPGIQGR KGEPGEGAYV YRSAFSVGLE TYVTIPNMPI RFTKIFYNQQ NHYDGSTGKF HCNIPGLYYF AYHITVYMKD VKVSLFKKDK AMLFTYDQYQ ENNVDQASGS VLLHLEVGDQ VWLQVYGEGE RNGLYADNDN DSTFTGFLLY HDTN
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