About Zinc finger and BTB domain-containing protein 6
Zinc finger and BTB domain-containing protein 6 (ZBTB6) is a protein
from Homo sapiens identified by UniProt accession
Q15916, 424 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 6 |
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| UniProt accession | Q15916 |
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| Gene | ZBTB6 |
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| Organism | Homo sapiens |
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| Length | 424 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (33)
Diseases linked to this target (Open Targets).
- body height · score 0.22
- type 2 diabetes mellitus · score 0.16
- HbA1c measurement · score 0.15
- insomnia measurement · score 0.12
- birth weight · score 0.10
- systolic blood pressure · score 0.09
- wellbeing measurement · score 0.09
- mean corpuscular volume · score 0.08
- neuroimaging measurement · score 0.08
- cortical thickness · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15916-F1 | alphafold | PREDICTED | 58.50 | — |
Amino-acid sequence (424 residues)
MAAESDVLHF QFEQQGDVVL QKMNLLRQQN LFCDVSIYIN DTEFQGHKVI LAACSTFMRD QFLLTQSKHV RITILQSAEV GRKLLLSCYT GALEVKRKEL LKYLTAASYL QMVHIVEKCT EALSKYLEID LSMKNNNQHT DLCQSSDPDV KNEDENSDKD CEIIEISEDS PVNIDFHVKE EESNALQSTV ESLTSERKEM KSPELSTVDI GFKDNEICIL HVESISTAGV ENGQFSQPCT SSKASMYFSE TQHSLINSTV ESRVAEVPGN QDQGLFCENT EGSYGTVSEI QNLEEGYSLR HQCPRCPRGF LHVENYLRHL KMHKLFLCLQ CGKTFTQKKN LNRHIRGHMG IRPFQCTVCL KTFTAKSTLQ DHLNIHSGDR PYKCHCCDMD FKHKSALKKH LTSVHGRSSG EKLSRPDLKR QSLL
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