About Zyxin
Zyxin (ZYX) is a protein
from Homo sapiens identified by UniProt accession
Q15942, 572 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | Zyxin |
|---|
| UniProt accession | Q15942 |
|---|
| Gene | ZYX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 572 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- basophil count · score 0.30
- monocyte count · score 0.30
- basophil percentage of leukocytes · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.25
- monocyte percentage of leukocytes · score 0.23
- basophil percentage of granulocytes · score 0.19
- calcium measurement · score 0.10
- ephrin type-A receptor 1 measurement · score 0.09
- hepatocellular carcinoma · score 0.08
- Ewing sarcoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q15942-F1 | alphafold | PREDICTED | 62.99 | — |
Amino-acid sequence (572 residues)
MAAPRPSPAI SVSVSAPAFY APQKKFGPVV APKPKVNPFR PGDSEPPPAP GAQRAQMGRV GEIPPPPPED FPLPPPPLAG DGDDAEGALG GAFPPPPPPI EESFPPAPLE EEIFPSPPPP PEEEGGPEAP IPPPPQPREK VSSIDLEIDS LSSLLDDMTK NDPFKARVSS GYVPPPVATP FSSKSSTKPA AGGTAPLPPW KSPSSSQPLP QVPAPAQSQT QFHVQPQPQP KPQVQLHVQS QTQPVSLANT QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE ALSAGTGSPQ PPSFTYAQQR EKPRVQEKQH PVPPPAQNQN QVRSPGAPGP LTLKEVEELE QLTQQLMQDM EHPQRQNVAV NELCGRCHQP LARAQPAVRA LGQLFHIACF TCHQCAQQLQ GQQFYSLEGA PYCEGCYTDT LEKCNTCGEP ITDRMLRATG KAYHPHCFTC VVCARPLEGT SFIVDQANRP HCVPDYHKQY APRCSVCSEP IMPEPGRDET VRVVALDKNF HMKCYKCEDC GKPLSIEADD NGCFPLDGHV LCRKCHTARA QT
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