About Heat shock protein beta-2
Heat shock protein beta-2 (HSPB2) is a protein
from Homo sapiens identified by UniProt accession
Q16082, 182 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Heat shock protein beta-2 |
|---|
| UniProt accession | Q16082 |
|---|
| Gene | HSPB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 182 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- BMI-adjusted hip circumference · score 0.23
- cardiovascular disease · score 0.08
- bladder transitional cell carcinoma · score 0.07
- systolic blood pressure · score 0.07
- neoplasm · score 0.07
- PR interval · score 0.06
- triglyceride measurement · score 0.05
- erythrocyte count · score 0.04
- birth weight · score 0.04
- Invasive Breast Carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16082-F1 | alphafold | PREDICTED | 74.52 | — |
Amino-acid sequence (182 residues)
MSGRSVPHAH PATAEYEFAN PSRLGEQRFG EGLLPEEILT PTLYHGYYVR PRAAPAGEGS RAGASELRLS EGKFQAFLDV SHFTPDEVTV RTVDNLLEVS ARHPQRLDRH GFVSREFCRT YVLPADVDPW RVRAALSHDG ILNLEAPRGG RHLDTEVNEV YISLLPAPPD PEEEEEAAIV EP
Explore Heat shock protein beta-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets